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- Title
Radiation-induced esophageal strictures treated with fluoroscopic balloon dilation: clinical outcomes and factors influencing recurrence in 62 patients.
- Authors
Park, Jung-Hoon; Kim, Kun Yung; Song, Ho-Young; Cho, Young Chul; Kim, Pyeong Hwa; Tsauo, Jiaywei; Kim, Min Tae; Jun, Eun Jung; Jung, Hwoon-Yong; Kim, Sung-Bae; Kim, Jong Hoon
- Abstract
Background Balloon dilation is safe and effective for the treatment of radiation-induced esophageal stricture (RIES), with favorable short-term and mid-term outcomes; however, few reports of long-term outcomes exist. Few studies have evaluated factors associated with recurrence after balloon dilation. Purpose To evaluate the long-term outcome of balloon dilation in patients with RIES and to identify factors associated with stricture recurrence. Material and Methods The medical records of 62 consecutive patients who had undergone fluoroscopic balloon dilation for RIES at our institution between December 1998 and June 2016 were reviewed. Results One hundred and twenty balloon dilation sessions were performed in 62 patients (mean = 1.9 sessions per patient). Clinical success was achieved in 53 (86%) patients after single (n = 37) or multiple (n = 16) dilation sessions. Complications occurred in 27% of the dilation sessions. The primary patency rates at one, two, three, and five years were 60%, 56%, 52%, and 52%, respectively. Secondary patency rates at one, two, three, and five years were 87%, 85%, 85%, and 80%, respectively. Multivariate logistic regression analysis identified an interval from radiation therapy (RT) to stricture of ≥6 months (hazard ratio [HR] = 0.205; P < 0.001), strictures located at the cervical esophagus (HR = 5.846; P < 0.001), and stricture length of ≥2 cm (HR = 2.923; P = 0.006) as significant predictors of recurrence. Conclusion Despite the high incidence of ruptures and recurrences, fluoroscopic balloon dilation is valuable as an initial therapeutic option for patients with RIES.
- Subjects
ESOPHAGEAL stenosis; FLUOROSCOPY; PATHOLOGICAL physiology; INTERVENTIONAL radiology; RADIATION injuries; DISEASE relapse; TREATMENT effectiveness; RETROSPECTIVE studies; DISEASE complications; THERAPEUTICS
- Publication
Acta Radiologica, 2018, Vol 59, Issue 3, p313
- ISSN
0284-1851
- Publication type
Article
- DOI
10.1177/0284185117713351