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- Title
Dose Response of Laboratory Markers to Alcohol Consumption in a General Population.
- Authors
Sillanaukee, Pekka; Massot, Nuria; Jousilahti, Pekka; Vartiainen, Erkki; Sundvall, Jouko; Olsson, Ulf; Poikolainen, Kari; Pönniö, Maritta; Allen, John P.; Alho, Hannu
- Abstract
The dose response to alcohol use of carbohydrate-deficient transferrin (CDT), γ-glutamyltransferase (GGT), and their combination (γ-CDT) was studied in an age- and gender-stratified, random sample from Finland in 1997. A linear association with a threshold between alcohol consumption and the three markers was observed. Body mass index was negatively associated with CDT and positively with GGT. Age was positively associated with GGT and γ-CDT. In conclusion, CDT appears to be an early phase marker of alcohol consumption. The combined marker, γ-CDT, was less associated with factors such as body mass index but more strongly correlated with alcohol consumption than were the two markers separately. Am J Epidemiol 2000;152:747–51.
- Subjects
PHYSIOLOGICAL effects of alcohol; TRANSFERRIN; ALCOHOL drinking; CARBOHYDRATES in the body; BODY mass index; AGE factors in disease
- Publication
American Journal of Epidemiology, 2000, Vol 152, Issue 8, p747
- ISSN
0002-9262
- Publication type
Article
- DOI
10.1093/aje/152.8.747