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- Title
Cap-assisted endoscopic mucosal resection as a salvage technique for challenging colorectal laterally spreading tumors.
- Authors
Michielan, Andrea; Crispino, Federica; de Pretis, Nicolò; Sartori, Chiara; Decarli, Nicola Libertà; de Pretis, Giovanni; Merola, Elettra
- Abstract
Background: Cap-assisted endoscopic mucosal resection (EMR-c) has emerged as a potential alternative to standard piecemeal wide-field EMR (WF-EMR) for the resection of laterally spreading tumors (LSTs). However, clear indications for this technique are still lacking. Our objective was to investigate the performance of salvage EMR-c after WF-EMR failure in the resection of large colorectal LSTs. Methods: The data of consecutive patients undergoing WF-EMR for large colorectal LSTs (2015–2021) were analyzed in this single-center, retrospective, observational study. In the event of a WF-EMR failure, the procedure was switched to EMR-c in the same session. The efficacy of the two techniques was evaluated in terms of complete endoscopic resection, R0 resection, and recurrence rate. Safety was also assessed. Results: Overall, the data from 81 WF-EMRs were collected. Eighteen cases of WF-EMR failure were switched to EMR-c in the same session and complete endoscopic resection was achieved in 17/18 patients (94.4%). No statistically significant difference was observed between WF-EMR and salvage EMR-c in terms of macroscopic radicality (P = 0.40) and R0 resection (P = 0.12). However, recurrence was more common with EMR-c (44.4% vs. 23.5%; P = 0.05), as were adverse events, particularly intraprocedural bleeding (27.8% vs. 7.9%; P = 0.04). Conclusion: EMR-c is an effective salvage technique for challenging colorectal LSTs following WF-EMR failure. Due to the elevated risk of adverse events associated with this procedure, careful patient selection, endoscopic expertise, and close follow-up are strongly recommended.
- Publication
Surgical Endoscopy & Other Interventional Techniques, 2023, Vol 37, Issue 10, p7859
- ISSN
1866-6817
- Publication type
Article
- DOI
10.1007/s00464-023-10347-9