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- Title
Cancer-Related Genetic Testing and Personalized Medicine for Adolescents: A Narrative Review of Impact and Understanding.
- Authors
Vetsch, Janine; Wakefield, Claire E.; Warby, Meera; Tucker, Katherine; Patterson, Pandora; McGill, Brittany C.; Metcalfe, Alison; Cohn, Richard J.; Fardell, Joanna E.
- Abstract
Genetic testing is becoming increasingly available for adolescents who are undergoing cancer treatment or at risk of cancer predisposition syndromes. With this narrative review, we aimed to synthesize the evidence on psychosocial outcomes and adolescents' understanding of genetic testing—thus far, an underresearched topic. Both psychological benefits and harms of predictive testing were reported in adolescents from high-risk families. Harms were mainly related to cancer-specific distress and increased worries. Findings on genetic understanding were sparse. Future studies should focus on psychosocial outcomes and adolescents' understanding undergoing genetic testing and enabling access to genetic counseling pre-testing and post-testing.
- Subjects
TUMOR diagnosis; TUMOR genetics; GENETIC testing; EARLY detection of cancer; FAMILIES; PSYCHOLOGICAL stress; TEENAGERS' conduct of life; PREDICTIVE tests; ADOLESCENCE; PSYCHOLOGY
- Publication
Journal of Adolescent & Young Adult Oncology, 2018, Vol 7, Issue 3, p259
- ISSN
2156-5333
- Publication type
Article
- DOI
10.1089/jayao.2017.0102