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- Title
Human Teeth Disease Detection Using Refractive Index Based Surface Plasmon Resonance Biosensor.
- Authors
Alam, Mohammad Khursheed; Dhasarathan, Vigneswaran; Natesan, Ayyanar; Nambi, Ramanujam; Zaman, Mahmud Uz; Ganji, Kiran Kumar; Basri, Rehana; Munisekhar, Manay Srinivas; Nagarajappa, Anil Kumar; Abutayyem, Huda
- Abstract
The paper proposes a surface plasmon resonance (SPR) biosensor utilizing MXene and a Molybdenum Disulfide (MoS2) material layer, placed on the Ag metal-based conventional biosensor to detect disease in human teeth. The SPR biosensor works on the principle of attenuated total reflection. The transverse matrix method was utilized for the reflectivity calculation. The thickness of the Ag layer, MXene, and MoS2 were taken as 45, 0.993, and 0.375 nm, respectively. Single-layer MoS2 and two layers of MXene were taken, and the highest sensitivity of the sensor for the enamel, dentin, and cementum was obtained at 83.219 deg/RIU, 91.460 deg/RIU, and 104.744 deg/RIU. MoS2 was used to enhance the biocompatibility of the analyte with the sensing layer. The aqueous solution had been considered as sensing medium.
- Subjects
SURFACE plasmon resonance; DENTAL pathology; REFRACTIVE index; ATTENUATED total reflectance; BIOSENSORS; MOLYBDENUM disulfide
- Publication
Coatings (2079-6412), 2022, Vol 12, Issue 10, p1398
- ISSN
2079-6412
- Publication type
Article
- DOI
10.3390/coatings12101398