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- Title
Unusual Presentation of Cutaneous Spindle Cell Squamous Cell Carcinoma: A Case Report.
- Authors
Wernheden, Erika; Trøstrup, Hannah; Pedersen Pilt, Anette
- Abstract
Cutaneous spindle cell squamous cell carcinoma (SpSCC) is a rare and often aggressive subtype of squamous cell carcinoma (SCC), which usually appears in sun-exposed areas, in areas that have received prior ionizing radiation, or in immunosuppressed individuals. SpSCCs are histologically characterized by keratinocytes infiltrating the dermis as single cells with elongated nuclei rather than as cohesive nests or islands and, in contrast to conventional SCC, are lacking features of keratinization. Immunohistochemical studies are useful to distinguish SpSCC from other spindle cell neoplasms, such as spindle cell/desmoplastic melanoma, cutaneous leiomyosarcoma, and atypical fibroxanthoma. We present a rare case of a patient with SpSCC in the gluteal region with regional lymph node metastasis. The patient was treated with wide excision of the tumor, inguinal lymph node dissection, and adjuvant radiotherapy. Cutaneous SpSCC is clinically similar to conventional SCC but can demonstrate more aggressive behavior. This case is rare since it was localized in the gluteal region of an otherwise healthy man.
- Subjects
SQUAMOUS cell carcinoma; BUTTOCKS; LYMPHADENECTOMY; IONIZING radiation; CELL nuclei
- Publication
Case Reports in Dermatology, 2020, Vol 12, Issue 1, p70
- ISSN
1662-6567
- Publication type
Article
- DOI
10.1159/000507358