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- Title
Albuminuria and cardiovascular risk in hypertensive patients with left ventricular hypertrophy: The LIFE Study.
- Authors
Ibsen, Hans; Kristian3 Wachtell; Olsen, Michael H.; Borch-Johnsen, Knut; Lindholm, Lars H.; Mogensen, Carl Erik; Dahlöf, Björn
- Abstract
Albuminuria and cardiovascular risk in hypertensive patients with left ventricular hypertrophy: The LIFE Study. Studies have shown that albuminuria is associated with increased risk for cardiovascular events. We tested the relationship between albuminuria (UACR) and cardiovascular risk in 8206 hypertensive patients with left ventricular hypertrophy included in the LIFE Study. Follow-up was 39,122 patient years. The risk for the primary composite cardiovascular end point increases continuously from the lowest to the highest decile of baseline UACR. No specific threshold could be identified. In conclusion, albuminuria predicts the outcome in the LIFE Study. The risk for cardiovascular morbidity and mortality among hypertensive patients with left ventricular hypertrophy increases at much lower UACR than has been reported in diabetic patients.
- Subjects
HYPERTENSION; ALBUMINURIA; CARDIOVASCULAR diseases; CARDIAC hypertrophy; KIDNEY diseases
- Publication
Kidney International Supplement, 2004, Issue 92, pS56
- ISSN
0098-6577
- Publication type
Article
- DOI
10.1111/j.1523-1755.2004.09214.x