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- Title
The Isolation of a New S -Methyl Benzothioate Compound from a Marine-Derived Streptomyces sp.
- Authors
Ainy Mahyudin, Nor; Blunt, John W.; Cole, Anthony L. J.; Munro, Murray H. G.
- Abstract
The application of an HPLC bioactivity profiling/microtiter plate technique in conjunction with microprobe NMR instrumentation and access to the AntiMarin database has led to the isolation of a new 1. In this example, 1 was isolated from a cytotoxic fraction of an extract obtained from marine-derived Streptomyces sp. cultured on Starch Casein Agar (SCA) medium. The 1D and 2D 1H NMR and ESIMS data obtained from 20 μg of compound 1 fully defined the structure. The known 2 was also isolated and readily dereplicated using this approach.
- Publication
Journal of Biomedicine & Biotechnology, 2012, Vol 2012, p1
- ISSN
1110-7243
- Publication type
Journal Article
- DOI
2012/894708