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- Title
Aerobic Exercise Alters Analgesia and Neurotrophin-3 Synthesis in an Animal Model of Chronic Widespread Pain.
- Authors
Sharma, Neena K.; Ryals, Janelle M.; Gajewski, Byron J.; Wright, Douglas E.
- Abstract
The article reports on the results of research which was conducted to examine the effects moderate-intensity aerobic exercise had on pain-like behavior and neurotrophin-3 (NT-3) in an animal model of widespread pain. Researchers evaluated 40 female mice using a repeated measures, observational cross-sectional study. They found that the moderate intensity aerobic exercise stimulated NT-3 synthesis in skeletal muscles in the mice and that it reduced cutaneous and deep tissue hyperalgesia which had been induced by acidic saline.
- Subjects
PAIN; ANALGESIA; MICE; HYPERALGESIA; LABORATORY mice; CHRONIC pain; ANIMAL models in research
- Publication
Physical Therapy, 2010, Vol 90, Issue 5, p714
- ISSN
0031-9023
- Publication type
Article
- DOI
10.2522/ptj.20090168