We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Association Between Factor V Leiden Mutation and the Hemiconvulsion, Hemiplegia, and Epilepsy Syndrome: report of Two Cases.
- Authors
Scantlebury, Morris H.; David, Michèle; Cannant, Lionel
- Abstract
The factor V Leiden mutation is the most common hereditary cause of venous thrombosis in our population. In the pediatric population, it has been associated with cerebrovascular thrombosis, cerebral palsy, and prosencephaly in neonates. We present two children with hemiconvulsion, hemiplegia, and epilepsy syndrome in whom the cause is likely attributable to the factor V Leiden mutation. We suggest that patients presenting with hemiconvulsion, hemiplegia, and epilepsy syndrome should be routinely investigated for factor V Leiden, and, if positive, careful consideration should be given to therapeutic and prophylactic anticoagulation as this may improve long-term outcome.
- Subjects
VENOUS thrombosis; GENETIC mutation; EPILEPSY; HEMIPLEGIA
- Publication
Journal of Child Neurology, 2002, Vol 17, Issue 9, p713
- ISSN
0883-0738
- Publication type
Article
- DOI
10.1177/088307380201700914