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- Title
European therapeutic trials in ANCA-associated systemic vasculitis: disease scoring, consensus regimens and proposed clinical trials.
- Authors
Rasmussen, N.; Jayne, D. R. W.; Abramowicz, D.; Andrassy, K.; Bacon, P. A.; Tervaert, J. W. Cohen; Dadonlené, J.; Feighery, C.; Van Es, L. A.; Ferrario, F.; Gaskin, G.; Gregorini, G.; de Groot, K.; Gross, W. L.; Grönhagen-Riska, C.; Guillevin, L.; Hagen, E. C.; Heigl, Z.; Hermans, J.; Kallenberg, C. G. M.
- Abstract
The article presents information on the European therapeutic trials in antineutrophil cytoplasmic antibodies-associated systemic vasculitis. The systemic vasculitides are a significant health issue in the European Union (EU) with an annual incidence of approximately 40 per million and estimated direct health costs to the EU of 500 million ECU per year. The relative rarity and heterogeneous nature of systemic vasculitis have impeded controlled clinical trials and dictate a mulidisciplinary and multicentre approach to their clinical investigation, which has been assisted by recent advances in classification and diagnosis.
- Subjects
VASCULITIS; CLINICAL trials; VASCULAR diseases; INFLAMMATION; MEDICAL research; IMMUNOGLOBULINS
- Publication
Clinical & Experimental Immunology, 1995, Vol 101, p29
- ISSN
0009-9104
- Publication type
Article
- DOI
10.1111/j.1365-2249.1995.tb06161.x