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- Title
Primary squamous cell carcinoma of the liver producing parathyroid hormone-related protein.
- Authors
Saito, Takahito; Harada, Kenichi; Tsuneyama, Koichi; Hirano, Masaaki; Amaya, Susumi; Sasaki, Motoko; Kaneko, Suichi; Kobayashi, Kenichi; Nakanuma, Yasuni; Amaya, Susumu; Kaneko, Shuichi
- Abstract
We report here an autopsy case of primary squamous cell carcinoma of the liver in a 63-year-old man who had hypercalcemia and an elevated serum level of parathyroid hormone-related protein. At autopsy, primary squamous cell carcinoma of the liver was found, without distinct preceding or associated hepatic or biliary diseases; no extrahepatic primary focus of squamous cell carcinoma was found. Bone involvement was not demonstrated, either radiologically or pathologically. Immunohistochemically, parathyroid hormone-related protein was detectable in the squamous cell carcinoma cells and it may have been responsible for the hypercalcemia. Such a case has not been reported so far in the English-language or the Japanese literature.
- Subjects
SQUAMOUS cell carcinoma; LIVER tumors; PARATHYROID hormone; HYPERCALCEMIA
- Publication
Journal of Gastroenterology, 2002, Vol 37, Issue 2, p138
- ISSN
0944-1174
- Publication type
journal article
- DOI
10.1007/s005350200010