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- Title
400Overactive bladder with/without urinary incontinence and falls in the community-dwelling elderly.
- Authors
Omae, Kenji; Kurita, Noriaki; Takeshima, Taro; Naganuma, Toru; Takahashi, Sei; Yoshioka, Takashi; Ohnishi, Tsuyoshi; Ito, Fumihito; Hamaguchi, Sugihiro; Fukuhara, Shunichi
- Abstract
Background Little is known about the fall risk of older adults with overactive bladder (OAB), especially in the absence of urgency incontinence (UI). Methods This prospective cohort study included 630 community-dwelling, independent older adults 75 years old or older who attended a health check-up in 2017 with a 1-year follow-up. The associations of OAB with and without UI (OAB-wet and OAB-dry) with a fall history, and future fall risk compared to no OAB were assessed using logistic regression models. The contribution of OAB as a predictor of falls was examined using a random forest and decision tree approach. Results Of the 577 analyzed participants (median age 79 years), 273 were men. The prevalence of OAB-dry and OAB-wet at baseline was 15% and 14%, respectively. Multivariable logistic regression analysis revealed that both OAB-dry and OAB-wet were associated with a higher likelihood of prior falls (adjusted ORs vs no OAB 2.03 and 2.21, respectively; 95% CI 1.23–3.37 and 1.29–3.78, respectively). Among the 363 participants without a fall history, the adjusted ORs (95% CIs) of OAB-dry and OAB-wet for the occurrence of falls during the 1-year follow-up were 2.74 (1.19–6.29) and 1.35 (0.47–3.87), respectively. The tree-based approach used for all participants showed that OAB was an important predictor of falls in adults without a fall history. Conclusions OAB, even in the absence of UI, is an important predictor of falls in older adults with a low absolute fall risk. Key messages Our findings suggest that OAB is a risk factor for falls in the community-dwelling elderly irrespective of the presence of UI.
- Subjects
OLDER people; URINARY incontinence; LOGISTIC regression analysis; ADULTS; RANDOM forest algorithms; OLDER men; FRAIL elderly
- Publication
International Journal of Epidemiology, 2021, Vol 50, p1
- ISSN
0300-5771
- Publication type
Article
- DOI
10.1093/ije/dyab168.513