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- Title
A comprehensive review of the effects of resveratrol on glucose metabolism: unveiling the molecular pathways and therapeutic potential in diabetes management.
- Authors
Moon, Dong-Oh
- Abstract
Resveratrol, a naturally occurring polyphenolic compound predominantly found in red wine and grapes, has garnered attention for its potential role in regulating carbohydrate digestion, glucose absorption, and metabolism. This review aims to deliver a comprehensive analysis of the molecular mechanisms and therapeutic potential of resveratrol in influencing vital processes in glucose homeostasis. These processes include carbohydrate digestion, glucose absorption, glycogen storage, insulin secretion, glucose metabolism in muscle cells, and triglyceride synthesis in adipocytes. The goal of this review is to offer an in-depth understanding of the multifaceted effects of resveratrol on glucose metabolism. By doing so, it presents valuable insights into its potential applications for preventing and treating metabolic disorders. This comprehensive examination of resveratrol's impact on glucose management will contribute to the growing body of knowledge on this promising natural compound, which may benefit researchers, healthcare professionals, and individuals interested in metabolic disorder prevention and treatment. Highlights: Resveratrol limits glucose absorption in the intestines. Resveratrol promotes glycogen formation in the liver. Resveratrol boosts insulin secretion in pancreatic cells, enhances insulin receptiveness in muscle cells, and inhibits triglyceride production in fat cells.
- Subjects
GLUCOSE metabolism; HOMEOSTASIS; FAT cells; MUSCLE metabolism; GRAPES; METABOLIC disorders; MEDICAL personnel
- Publication
Molecular Biology Reports, 2023, Vol 50, Issue 10, p8743
- ISSN
0301-4851
- Publication type
Article
- DOI
10.1007/s11033-023-08746-1