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- Title
Refractory Takayasu's Arteritis with Severe Coronary Involvement—Case Report and Literature Review.
- Authors
Cobilinschi, Claudia Oana; Grădinaru, Elena; Săulescu, Ioana; Cârstea, Nicolae; Caraiola, Simona; Bălănescu, Andra Rodica; Opriș-Belinski, Daniela
- Abstract
This report presents the case of a female patient diagnosed with Takayasu arteritis from childhood, with severe, refractory coronary involvement, leading to two acute coronary syndromes and multiple anginous episodes. Consequently, the patient suffered aorto-bicarotid bypass two times, multiple interventional procedures with stent implantation, balloon angioplasty, and up to ten repeated in-stent restenosis that required reinterventions, despite being on maximal immunosuppressive treatment. In recent years, various studies have been reported that aim to best characterize this particular type of vascular damage and to indicate optimal therapeutic options for treatment. The latter should be based on the activity of the underlying disease; however, no reliable markers are available in TA. The management of TA patients with coronary involvement continues to be a challenge and requires both drug and interventional techniques to avoid life-threatening events.
- Subjects
LITERATURE reviews; ACUTE coronary syndrome; TRANSLUMINAL angioplasty; TAKAYASU arteritis; REFRACTORY materials; ANGINA pectoris
- Publication
Journal of Clinical Medicine, 2023, Vol 12, Issue 13, p4394
- ISSN
2077-0383
- Publication type
Case Study
- DOI
10.3390/jcm12134394