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- Title
Polymorphisms in candidate genes as markers for sperm quality and boar fertility.
- Authors
Wimmers, K.; Lin, C. L.; Tholen, E.; Jennen, D. G. J.; Schellander, K.; Ponsuksili, S.
- Abstract
α-Actinins (ACTN1andACTN4) andγ-actin (ACTG2), were investigated as candidate genes on the basis of their known functions, for their possible association with sperm concentration, motility, semen volume per ejaculate, plasma droplets rate, abnormal sperm rate and the fertility traits, non-return rate and number of piglets born alive. Polymorphisms were identified in intron 18 (G>A) of the porcineACTN1gene and in exon 22 (A>C) of the porcineACTN4gene by comparative sequencing of animals from the Pietrain (PI) and Hampshire (HA) breeds. Pietrain (n = 244) and crossbreed PI × HA (n = 112) boars from an artificial insemination boar station were genotyped for the single nucleotide polymorphisms (SNPs) withinACTN1andACTN4as well as for a previously described microsatellite withinACTG2. The study provides evidence for effects ofACTN1on fertility and ofACTG2on sperm quality traits, while no indication of impact ofACTN4on any of these traits was found.
- Subjects
GENETIC polymorphisms; POPULATION genetics; SPERMATOZOA; GENES; NUCLEOTIDES
- Publication
Animal Genetics, 2005, Vol 36, Issue 2, p152
- ISSN
0268-9146
- Publication type
Article
- DOI
10.1111/j.1365-2052.2005.01267.x