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- Title
Anemia hemolítica como presentación inicial de la enfermedad de Wilson: A propósito de una enfermedad rara con una presentación infrecuente.
- Authors
MAURICIO GALVEZ-CÁRDENAS, KENNY; MAURICIO SANTOS-SÁNCHEZ, ÓSCAR; ALEJANDRO MEDINA-MORALES, DIEGO
- Abstract
Wilson's disease is a rare genetic disorder that affects the excretion capacity of copper. Its distribution is worldwide, with an estimated prevalence in 30 cases per million habitants. Although the most frequent symptoms are those of hepatic and neuropsychiatric origin, hemolytic anemia with negative Coombs may be the only manifestation of the disease and its presentation usually precedes for months to clinically evident liver disease or neurological manifestations. The case of a young patient with negative Coombs hemolytic anemia and an alkaline phosphatase / total bilirubin ratio <4 and AST / ALT> 2.2 is presented, establishing Wilson's disease as a diagnosis.
- Publication
Acta Medica Colombiana, 2020, Vol 45, Issue 1, p1
- ISSN
0120-2448
- Publication type
Article
- DOI
10.36104/amc.2020.1459