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- Title
Antioxidant profile of constituents isolated from Polygonatumverticillatum rhizomes.
- Authors
Khan, Haroon; Saeed, Muhammad; Muhammad, Naveed; Rauf, Abdur; Khan, Amir Zada; Ullah, Rooh
- Abstract
The purpose of the current study was to estimate the antioxidant profile of two compounds, diosgenin and santonin, isolated from Polygonatumverticillatum rhizomes. Stable free radical, 2, 2-diphenyl-1-picrylhydrazyl and reducing power assays were employed for this purpose. The results showed profound free radical scavenging effect of both diosgenin and santonin in a concentration-dependent manner. The calculated half maximal inhibitory concentration (IC50) values for both diosgenin and santonin was 65.80 and 50.03 μg/ml, respectively. Similarly, in reducing power assay, diosgenin and santonin exhibited marked quenching effect. The corresponding IC50 values for both the compounds were 62.10 and 46.40 μg/ml, respectively. In conclusion, both the isolated compounds have strong antioxidant potential, which is consistent with the results of the extracts of the plant.
- Subjects
SOLOMON'S seal; PHYSIOLOGICAL effects of antioxidants; DIOSGENIN; PLANT extracts; SANTONIN
- Publication
Toxicology & Industrial Health, 2016, Vol 32, Issue 1, p138
- ISSN
0748-2337
- Publication type
Article
- DOI
10.1177/0748233713498454