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- Title
Susceptibility of Human T Cell Leukemia Virus Type I to Nucleoside Reverse Transcriptase Inhibitors.
- Authors
Hill, Shawn A.; Lloyd, Patricia A.; McDonald, Shannon; Wykoff, Jennifer; Derse, David
- Abstract
A single-cycle infection assay with recombinant viral vectors was developed to study human T cell leukemia virus type I (HTLV-I) replication and its inhibition by antiviral agents. The susceptibility of HTLV-I to 6 nucleoside reverse-transcriptase inhibitors was examined. HTLV-I replication was inhibited by tenofovir, abacavir, lamivudine, zalcitabine, stavudine, and zidovudine.
- Subjects
HTLV-I; REVERSE transcriptase
- Publication
Journal of Infectious Diseases, 2003, Vol 188, Issue 3, p424
- ISSN
0022-1899
- Publication type
Article
- DOI
10.1086/376531