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- Title
Voltage-gated calcium channels in epilepsy.
- Authors
Cain, Stuart M.; Snutch, Terrance P.
- Abstract
Voltage-gated calcium channels contribute to the control of excitability at both the cellular and neural network levels. Alterations in the expression or biophysical properties of specific subtypes of calcium channels can have pathophysiologic effects on the frequency and patterns of action potential firing and causally contribute to epileptic seizures. For an expanded treatment of this topic see Jasper's Basic Mechanisms of the Epilepsies, Fourth Edition (Noebels JL, Avoli M, Rogawski MA, Olsen RW, Delgado-Escueta AV, eds), published by Oxford University Press (available on the National Library of Medicine Bookshelf [NCBI] at ).
- Subjects
EPILEPSY; CALCIUM channels; DEVELOPMENTAL disabilities; BRAIN diseases; SPASMS
- Publication
Epilepsia (Series 4), 2010, Vol 51, p11
- ISSN
0013-9580
- Publication type
Article
- DOI
10.1111/j.1528-1167.2010.02797.x