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- Title
Heparin-Induced Thrombocytopenia An Iatrogenic Catastrophe.
- Authors
Dupont, Elisabeth L.; Gahtan, Vivian; Mills, Joseph L.
- Abstract
Serious limb- and life-threatening thromboembolic complications may result from immune-mediated, heparin-induced thrombocytopenia (HIT) type II. The authors describe three such cases associated with devastating outcomes. The clinical diagnosis of HIT II was based on (1) falling platelet count on heparin (<150,000/mm³), (2) thromboembolic events on heparin, and (3) absence of new thrombotic events after heparin discontinuation. These distinct case presentations are discussed to broaden clinical awareness of HIT II. A high index of suspicion is warranted to prevent this catastrophic complication.
- Subjects
THROMBOCYTOPENIA; IATROGENIC diseases; DRUG side effects; HEPARIN; ANTICOAGULANTS; BLOOD platelet disorders; THERAPEUTIC complications
- Publication
Vascular Surgery, 1999, Vol 33, Issue 1, p43
- ISSN
0042-2835
- Publication type
Article
- DOI
10.1177/153857449903300109