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- Title
Prophylaxis with Tixagevimab/Cilgavimab in chronic lymphocytic leukaemia, a case control study.
- Authors
Guarnera, Luca; Tiravanti, Ilaria; Guiducci, Arianna; Coppola, Luigi; Marinoni, Massimiliano; Nunzi, Andrea; Laureana, Roberta; Cardillo, Lucia; Esposito, Fabiana; Secchi, Roberto; Buzzatti, Elisa; Paterno, Giovangiacinto; Pupo, Livio; Sarmati, Loredana; Gattei, Valter; Venditti, Adriano; Postorino, Massimiliano; Del Principe, Maria Ilaria
- Abstract
A case-control study was conducted to evaluate the efficacy of Tixagevimab/Cilgavimab prophylaxis in preventing SARS-CoV2 infection in patients with chronic lymphocytic leukemia (CLL). The study included 83 patients, with 53 receiving prophylaxis and 30 in the control group. The results showed that the infection rate was not significantly different between the two groups, and there were no significant differences in the symptomatic picture, duration of infection, or rate of hospitalization. The study suggests that wider, prospective trials are needed to determine the best strategy for preventing COVID-19 infection in CLL patients.
- Subjects
SARS-CoV-2 Omicron variant; BLOOD cell count; LYMPHOCYTIC leukemia; COVID-19; HEMATOLOGIC malignancies
- Publication
Annals of Hematology, 2024, Vol 103, Issue 9, p3831
- ISSN
0939-5555
- Publication type
Letter
- DOI
10.1007/s00277-024-05815-8