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- Title
Effects of Exercise on Cardiac Oxidative Stress in Rats after Exposure to Cigarette Smoke.
- Authors
Veloso, Carolina Fantinel; Costa, Carolina Dalla; Rovani, Bruno Tomazeli; da Costa Araldi, Isabel Cristina; de Freitas, Robson Borba; Cogo, Lícia Assunção; da Silveira, Aron Ferreira; de Freitas Bauermann, Liliane; da Silva, Antônio Marcos Vargas
- Abstract
The aim of this study was to evaluate the influence of physical exercise on the levels of oxidative stress in cardiac tissue after the inhalation of cigarette smoke in rats. Rats were divided into four groups: (a) non-smokers + non-exercised (NS+NE); (b) non-smokers + exercised (NS+E); (c) smokers + non-exercised (S+NE); and (d) smokers + exercised (S+E). The cigarette smoke was inhaled during 30 min, twice a day, and then extended to 10 cigarettes for 30 min twice a day. Physical exercise was performed on a treadmill. The initial velocity was 10 m·min-1 increasing up to the mark of 30 m·min-1. Cardiac tissue lipoperoxidation (LPO) estimation was performed using the TBARS method. The values were expressed in levels of malondialdehyde (MDA), and enzymatic antioxidant defense was measured by catalase (CAT) activity. These findings indicate that the physical exercise induced lower levels of LPO and increased CAT activity, which attenuated the oxidative stress induced by exposure to cigarette smoke.
- Subjects
OXIDATIVE stress; HEART diseases; LABORATORY rats; CIGARETTE smoke; TREADMILL exercise; MALONDIALDEHYDE
- Publication
Journal of Exercise Physiology Online, 2013, Vol 16, Issue 5, p21
- ISSN
1097-9751
- Publication type
Article