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- Title
Neonatal gastrointestinal perforation in Japan: a nationwide survey.
- Authors
Sato, Masahito; Hamada, Yoshinori; Kohno, Miyuki; Ise, Kazuya; Uchida, Keiichi; Ogata, Hiromi; Masuyama, Hiroaki; Morotomi, Yoshiki; Yasufuku, Masao; Wada, Motoshi
- Abstract
<bold>Purpose: </bold>The purpose of this study is to identify the current clinical features of neonatal gastrointestinal perforation in Japan.<bold>Methods: </bold>A questionnaire about cases of neonatal gastrointestinal perforation treated in recent 5 years was sent to participating institutions of the Japanese Society of Pediatric Surgeons (JSPS).<bold>Results: </bold>Five hundred and thirty-six neonates with gastrointestinal perforation were treated. They consisted of 42 patients with gastric rupture/perforation (GR), 33 patients with intestinal atresia/stenosis (IA), 3 patients with malrotation (ML), 118 patients with necrotizing enterocolitis (NEC), 160 patients with focal intestinal perforation (FIP), 46 patients with meconium-related ileus (MRI), 77 patients with meconium peritonitis (MP), and 57 patients with other conditions. The total mortality rate was 20.5 %. The mortality rates of the patients with GR, IA, ML, NEC, FIP, MRI, and MP were 9.5, 9.1, 0, 33.1, 20.6, 28.2, and 9.1 %, respectively. In 263 cases involving extremely low-birth-weight neonates (ELBW), 108 died (mortality rate 41.1 %). The mortality rates for ELBW with GR, NEC, FIP, MRI, MP, and other conditions were 27.3 % (3/11), 58.5 % (48/82), 21.6 % (24/111), 70.6 % (24/34), 57.1 % (4/7), and 27.8 % (5/18), respectively.<bold>Conclusions: </bold>The mortality rates for ELBW decreased from 62.8 % in the previous survey to 41.1 % by the time of this survey.
- Subjects
JAPAN; NEONATAL necrotizing enterocolitis; PEDIATRIC surgeons; GASTROINTESTINAL system; PERITONITIS; INTESTINAL perforation
- Publication
Pediatric Surgery International, 2017, Vol 33, Issue 1, p33
- ISSN
0179-0358
- Publication type
journal article
- DOI
10.1007/s00383-016-3985-z