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- Title
Chequerboard titrations: the influence of the composition of serial dilutions of antibiotics on the fractional inhibitory concentration index and fractional bactericidal concentration index.
- Authors
Horrevorts, A. M.; de Ridder, C. M.; Poot, M. C.; de Jonge, M. J. A.; Degener, J. E.; Dzoljic-Danilovic, G.; Michel, M. F.; Kerrebijn, K. F.; de Jonge, M J
- Abstract
Chequerboard titrations carried out with modified serial dilutions of antibiotics such that consecutive concentrations in these series were four times smaller than those in two-fold serial dilutions enable MICs and MBCs to be determined with greater accuracy. Interaction indices calculated by this method can differ markedly from those calculated on the basis of two-fold serial dilutions. The differences calculated in this study ranged from −0.30 to + 1.06.
- Publication
Journal of Antimicrobial Chemotherapy (JAC), 1987, Vol 19, Issue 1, p119
- ISSN
0305-7453
- Publication type
journal article