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- Title
3D 打印技术在肝硬化门静脉高压并消化道出血患者 TIPS 中的应用.
- Authors
刘燚隆; 张 凯; 刘晶磊; 郭争荣; 党荣广
- Abstract
t To investigate the feasibility of 3D printing technology in transjugular intrahepatic portosystemic shunt (TIPS) for the patients with cirrhotic portal hypertension and gastrointestinal bleeding. Sixty patients with cirrhotic portal hypertension and gastrointestinal bleeding to be treated with TIPS in some hospital from March 2019 to September 2021 were selected for a prospective study and randomly divided into control and observation groups, with 30 cases in each group. The control group adopted conventional TIPS, while the observation group used the TIPS guided by 3D printing technology. The two groups were compared on the intraoperative radiation exposure dose, number of portal vein puncture stitches, ideal puncture location, change of portal vein pressure gradient before and after surgery, operation time, liver and kidney functions involving in AST, ALT, ALB, TBIL, DBIL, BUN, Scr and blood ammonia levels and the incidence of complications. SPSS 25.0 software was used for statistical analysis. The observation group had less intraoperative radiation exposure dose, number of portal vein puncture stitches and operation time (P<0.05) while higher ideal rate for puncture location than the control group (P<0.05). In both the groups the postoperative portal pressure gradients were lower than those before surgery (P<0.05). AST, ALT, blood ammonia and ALB levels in the 2 groups were higher than before surgery at 3 d, 7 d and 1 month after surgery (P<0.05), and BUN level was lower than before surgery (P<0.05), and TBIL and Scr levels at 3 d postoperatively and DBIL level at 3 d and 7 d postoperatively were higher than those before surgery (P<0.05), and TBIL and Scr levels at 1 month postoperatively were lower than those before surgery (P<0.05); AST, ALT, TBIL, DBIL, Scr and blood ammonia levels in the 2 groups decreased sequentially at 3 d, 7 d and 1 month after surgery (P<0.05), while ALB level increased sequentially (P<0.05); AST, ALT, ALB, TBIL, DBIL, BUN, Scr and blood ammonia levels in the observation group before and 3 d, 7 d, and 1 month after surgery were not statistically different with those of the control group (P>0.05). The overall incidence of complications in the observation group was lower than that in the control group (P<0.05). The involvement of 3D printing technology for guidance during TIPS in patients with cirrhotic portal hypertension and gastrointestinal bleeding contribute to decreasing the dose of radiation exposure, the number of portal vein puncture stitches, the operation time and the number of intraoperative and postoperative complications.
- Publication
Chinese Medical Equipment Journal, 2022, Vol 43, Issue 11, p54
- ISSN
1003-8868
- Publication type
Article
- DOI
10.19745/j.1003-8868.2022230