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- Title
Device to Collect Skin Cells Using Ultrasound Irradiation and Aspiration.
- Authors
Yang Ye; Tatsuya Uechi; Noriko Tsuruoka; Makoto Akashi; Yoichi Haga
- Abstract
Dynamic cell activity can be examined by collecting and analyzing cells every few hours during the day. However, current techniques to extract and analyze skin cells are deemed ineffective and/or invasive. Thus, in this study, we designed and fabricated a device that collects skin cells using ultrasound irradiation. An ultrasonic horn amplifies a Langevin transducer, which then generates ultrasound and transmits it to a fine needle. Ultrasound is irradiated from the needle to the body surface, and ultrasonic oscillation and cavitation cut or weaken intercellular binding. We successfully aspirated 30 cells from pig skin using our minimally invasive device.
- Subjects
ULTRASONIC imaging; IRRADIATION; TRANSDUCERS; CAVITATION; ULTRASONICS; VIDEOFLUOROSCOPY
- Publication
Sensors & Materials, 2022, Vol 34, Issue 9, Part 1, p3383
- ISSN
0914-4935
- Publication type
Article
- DOI
10.18494/SAM3983