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- Title
Heat-Killed L. helveticus Enhances Positive Mood States: A Randomized, Double-Blind, Placebo-Controlled Study.
- Authors
Mutoh, Natsumi; Kakiuchi, Izumi; Kato, Kumiko; Xu, Chendong; Iwabuchi, Noriyuki; Ayukawa, Masayo; Kiyosawa, Kyoko; Igarashi, Kazumi; Tanaka, Miyuki; Nakamura, Masahiko; Miyasaka, Mitsunaga
- Abstract
When mood states are impaired, daily life is severely disrupted. To maintain a specific mood state, both positive and negative moods must be controlled; however, methods to maintain a positive mood have not been fully established. Previous studies have suggested that heat-killed L. helveticus MCC1848 has the potential to improve positive moods. This study aimed to test the efficacy of heat-killed L. helveticus MCC1848 in maintaining and improving a positive mood with PANAS, a questionnaire specifically designed to assess positive and negative mood, as the primary endpoint. Healthy Japanese nursing students (n = 46) were randomized to receive heat-killed L. helveticus MCC1848 (5 billion/day) or placebo powder for four weeks. Mood state was assessed before and two and four weeks after the intervention began; ingestion of heat-killed L. helveticus MCC1848 significantly improved PANAS 'Positive Affect' compared to the placebo. These results indicate that heat-killed L. helveticus MCC1848 is effective in enhancing positive mood.
- Subjects
JAPANESE students; NURSING students; AFFECT (Psychology); QUESTIONNAIRES; INGESTION
- Publication
Brain Sciences (2076-3425), 2023, Vol 13, Issue 6, p973
- ISSN
2076-3425
- Publication type
Article
- DOI
10.3390/brainsci13060973