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- Title
Targeted Tailored Management of the Breast Cancer Patient at Risk for Harboring a Germline Mutation—Current Trends Affecting the Selection of Patients Considering Surgical Prophylaxis for Breast Cancer.
- Authors
Silva, Edibaldo
- Abstract
Recent reports have documented the increasing use of mastectomy in women with breast cancer otherwise amenable to breast conservation. Similarly, other reports document an increase in the number of women undergoing contra-lateral prophylactic mastectomy for a single unilateral breast cancer. These trends are abetted by increasing use of MRI, inadequate risk counseling, and patient fear. Adequate and reliable risk assessment and genetic counseling are indispensable for the appropriate and personalized treatment of these individuals. In all of these instances, such counseling should be instituted well before the patients are submitted to any surgical intervention. An algorithm is presented which permits the orderly selection of patients who may benefit from such aggressive surgical intervention.
- Subjects
BREAST cancer patients; MASTECTOMY; GENETIC mutation; ALGORITHMS; GENETIC counseling
- Publication
Breast Journal, 2009, Vol 15, pS76
- ISSN
1075-122X
- Publication type
Article
- DOI
10.1111/j.1524-4741.2009.00795.x