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- Title
Use of cidofovir in polyomavirus BK viral nephropathy in two renal allograft recipients.
- Authors
Lim, Wai H.; Mathew, Timothy H.; Cooper, John E.; Bwoden, Scott; Russ, Grame R.
- Abstract
Polyomavirus BK viral allograft nephropathy is a potentially reversible cause of deteriorating function of kidney allografts. Initial treatment involves reducing immunosuppressive medications, with low-dose cidofovir an effective alternative in refractory cases. We describe two cases of BK viral allograft nephropathy responding to low-dose cidofovir after a reduction in immunosuppressive medications failed to clear the virus or stabilize the deterioration in renal function. There were no significant side-effects from this treatment in either patient.
- Subjects
POLYOMAVIRUSES; KIDNEY diseases; THERAPEUTICS; KIDNEY transplantation; IMMUNOSUPPRESSION
- Publication
Nephrology, 2003, Vol 8, Issue 6, p318
- ISSN
1320-5358
- Publication type
Article
- DOI
10.1111/j.1440-1797.2008.00214.x