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- Title
Coculture between periosteal explants and articular chondrocytes induces expression of TGF-β1 and collagen I.
- Authors
Grässel, Susanne; Rickert, Matthias; Opolka, Alfred; Bosserhoff, Anja; Angele, Peter; Grifka, Joachim; Anders, Sven
- Abstract
Objective. Repair of focal articular cartilage lesions is usually performed by employing cell-based therapeutic strategies such as autologous chondrocyte implantation (ACI). The aim of this study was to determine whether periosteum exerts pro-chondrogenic effects on the transplanted cells beyond its biomechanical role in ACI.
- Subjects
CARTILAGE; CARTILAGE cells; PERIOSTEUM; TRANSFORMING growth factors; GENE expression
- Publication
Rheumatology, 2010, Vol 49, Issue 2, p218
- ISSN
1462-0324
- Publication type
Article
- DOI
10.1093/rheumatology/kep326