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- Title
The Possible Role of Flavonoids in the Prevention of Diabetic Complications.
- Authors
Testa, Roberto; Bonfigli, Anna Rita; Genovese, Stefano; De Nigris, Valeria; Ceriello, Antonio
- Abstract
Type 2 diabetes mellitus is a disease that affects many metabolic pathways. It is associated with insulin resistance, impaired insulin signaling, β‐cell dysfunction, abnormal glucose levels, altered lipid metabolism, sub‐clinical inflammation and increased oxidative stress. These and other unknown mechanisms lead to micro‐ and macro‐complications, such as neuropathy, retinopathy, nephropathy and cardiovascular disease. Based on several in vitro animal models and some human studies, flavonoids appear to play a role in many of the metabolic processes involved in type 2 diabetes mellitus. In this review, we seek to highlight the most recent papers focusing on the relationship between flavonoids and main diabetic complications.
- Publication
Nutrients, 2016, Vol 8, Issue 5, p1
- ISSN
2072-6643
- Publication type
Article
- DOI
10.3390/nu8050310