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- Title
Direct One-Pot Synthesis of Naphthoxindoles from 4-Bromooxindoles by Suzuki-Miyaura Coupling and Aldol Condensation Reactions.
- Authors
Park, Kyeong‐Yong; Kim, Bum Tae; Heo, Jung‐Nyoung
- Abstract
An efficient one-pot synthesis of naphthoxindoles by using 4-bromoindolin-2-ones and 2-formylphenylboronic acids has been developed. The coupling reaction proceeds in good to excellent yields under microwave irradiation through a Suzuki-Miyaura coupling and an aldol condensation cascade reaction. In addition, this protocol permits the facile construction of naphthoxindoles through an expanded scope of substrates.
- Subjects
CHEMICAL synthesis; BORONIC acids; COUPLING reactions (Chemistry); IRRADIATION; CONDENSATION; SUBSTRATES (Materials science)
- Publication
European Journal of Organic Chemistry, 2014, Vol 2014, Issue 1, p164
- ISSN
1434-193X
- Publication type
Article
- DOI
10.1002/ejoc.201301242