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- Title
Long-Acting Treatments for Hepatitis B.
- Authors
Thomas, David L; Kiser, Jennifer J; Baum, Marc M
- Abstract
There are an estimated 257 million persons living with chronic hepatitis B for whom there are multiple potential applications of long-acting antiviral compounds. Current efforts include both injection and implant approaches to formulating derivates of existing anti-HBV compounds such as tenofovir or entecavir. Substantial progress has already occurred especially as aligned with the development of long-acting tenofovir-based medications with dual activity against human immunodeficiency virus (HIV) and hepatitis B virus (HBV). Nonetheless, substantial challenges will need to be overcome before these agents are available.
- Subjects
HEPATITIS B; DRUG delivery systems; INJECTIONS; ANTIRETROVIRAL agents; CONTROLLED release drugs; HIGHLY active antiretroviral therapy; MEDICAL research
- Publication
Clinical Infectious Diseases, 2022, Vol 75, pS517
- ISSN
1058-4838
- Publication type
Article
- DOI
10.1093/cid/ciac718