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- Title
Liver Fibrosis Progression and Mortality in Hepatitis B– and C–Coinfected Persons Treated With Directly Acting Antiviral Agents: Results From ERCHIVES.
- Authors
Butt, Adeel A; Yan, Peng; Aslam, Samia; Abou-Samra, Abdul-Badi; Sherman, Kenneth E; Shaikh, Obaid S
- Abstract
For persons with baseline Fibrosis-4 1.46–3.25, cirrhosis incidence/1000 patient-years was 49.3 among hepatitis B virus (HBV)/hepatitis C virus (HCV) coinfected and 18.2 among HCV monoinfected (P =.03). Cirrhosis risk was numerically higher but statistically nonsignificant among HBV/HCV coinfected (hazards ratio [HR] 1.51; 95% confidence intervals [CI],.37–6.05) but lower among those who attained sustained virologic response (HR,.52; 95% CI,.42–.63).
- Subjects
ANTIVIRAL agents; CONFIDENCE intervals; DISEASE complications; HEPATITIS B; HEPATITIS C; LIVER; CIRRHOSIS of the liver; COMORBIDITY; FIBROSIS; TREATMENT effectiveness; DISEASE progression; DESCRIPTIVE statistics; DISEASE risk factors
- Publication
Clinical Infectious Diseases, 2020, Vol 71, Issue 3, p664
- ISSN
1058-4838
- Publication type
Article
- DOI
10.1093/cid/ciz1097