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- Title
Culture Conversion at 6 Months in Patients Receiving Delamanid-containing Regimens for the Treatment of Multidrug-resistant Tuberculosis.
- Authors
Seung, Kwonjune J; Khan, Palwasha; Franke, Molly F; Ahmed, Saman; Aiylchiev, Stalbek; Alam, Manzur; Putri, Fauziah Asnely; Bastard, Mathieu; Docteur, Wisny; Gottlieb, Gary; Hewison, Catherine; Islam, Shirajul; Khachatryan, Naira; Kotrikadze, Tinatin; Khan, Uzma; Kumsa, Andargachew; Lecca, Leonid; Tassew, Yoseph Melaku; Melikyan, Nara; Naing, Ye Yint
- Abstract
Delamanid should be effective against highly resistant strains of Mycobacterium tuberculosis , but uptake has been slow globally. In the endTB (expand new drug markets for TB) Observational Study, which enrolled a large, heterogeneous cohorts of patients receiving delamanid as part of a multidrug regimen, 80% of participants experienced sputum culture conversion within 6 months. Clinical Trials Registration. NCT02754765.
- Subjects
ANTITUBERCULAR agents; IMIDAZOLES; MICROBIAL sensitivity tests; SPUTUM; TIME
- Publication
Clinical Infectious Diseases, 2020, Vol 71, Issue 2, p415
- ISSN
1058-4838
- Publication type
Article
- DOI
10.1093/cid/ciz1084