We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Retrospective analysis of 1-year mortality after gastric cancer surgery: Total intravenous anesthesia versus volatile anesthesia.
- Authors
Oh, Tak Kyu; Kim, Hyung‐Ho; Jeon, Young‐Tae; Kim, Hyung-Ho; Jeon, Young-Tae
- Abstract
<bold>Background: </bold>It remains controversial whether propofol-based total intravenous anesthesia (TIVA) or inhalation anesthesia is associated with better outcomes after cancer surgery. We investigated whether there is a difference in the 1-year overall or cancer-related mortality between propofol-based TIVA and inhalation anesthesia in patients who underwent gastric cancer surgery.<bold>Methods: </bold>This retrospective cohort study was based on medical records of ll patients aged ≥18 years who underwent elective gastric cancer surgery with curative intent between January 2005 and December 2015 at a single tertiary academic hospital. Propensity score (PS) matching and Cox proportional hazard models were used for analyses.<bold>Results: </bold>After PS matching, 1538 patients (769 patients in each group) were included in the final analysis. The 1-year overall mortality risk was not significantly different between the TIVA and inhalation groups in either the PS-matched analysis [hazard ratio (HR): 0.92, 95% confidence interval (CI): 0.52-1.64; P = 0.774] or entire cohorts (HR: 0.82 95% CI: 0.52-1.33; P = 0.417) after multivariable adjustment. The 1-year cancer-related mortality risk was similar between the groups in both the PS-matched cohort (HR: 0.91, 95% CI: 0.50-1.67; P = 0.764) and the entire cohort after multivariable adjustment (HR: 0.82, 95% CI: 0.50-1.33; P = 0.406).<bold>Conclusions: </bold>We show that propofol-based TIVA was not significantly associated with a decrease in the 1-year overall or cancer-related mortality after gastric cancer surgery, as compared with inhalation anesthesia. Further studies are required to ascertain the optimal anesthetic choice for gastric cancer surgery.
- Subjects
INTRAVENOUS anesthesia; ONCOLOGIC surgery; STOMACH cancer; CANCER-related mortality; PROPORTIONAL hazards models; INHALATION anesthesia; COMPARATIVE studies; DIGESTIVE organ surgery; INTRAVENOUS anesthetics; LONGITUDINAL method; RESEARCH methodology; MEDICAL cooperation; PROBABILITY theory; RESEARCH; RISK assessment; STOMACH tumors; SURVIVAL analysis (Biometry); EVALUATION research; PROPOFOL; INHALATION anesthetics
- Publication
Acta Anaesthesiologica Scandinavica, 2019, Vol 63, Issue 9, p1169
- ISSN
0001-5172
- Publication type
journal article
- DOI
10.1111/aas.13414