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- Title
Cell-Permeable Peptide Inhibitors of JNK.
- Authors
Bonny, Christophe; Oberson, Anne; Negri, Stephanie; Sauser, Christelle; Schorderet, Daniel F.
- Abstract
Demonstrates that inhibition of c-Jun NH[sub 2]-terminal kinase (JNK) signaling with the use of islet-brain (IB) proteins 1 and 2 prevented interleukin (IL)-1beta-induced pancreatic beta-cell death. Domain of IB-1 that prevents beta-cell death; Synthesis of cell-permeable JNK-inhibitory peptides; JNK-inhibition in vitro.
- Subjects
ENZYME inhibitors; CELLULAR signal transduction; ISLANDS of Langerhans; INTERLEUKIN-1; CELL death; PHYSIOLOGY
- Publication
Diabetes, 2001, Vol 50, Issue 1, p77
- ISSN
0012-1797
- Publication type
Article
- DOI
10.2337/diabetes.50.1.77