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- Title
The Interaction of Acute Kidney Injury with Resuscitation Strategy in Sepsis: A Secondary Analysis of a Multicenter, Phase 3, Randomized Clinical Trial (CLOVERS).
- Authors
Khader, Ayesha; Zelnick, Leila R.; Sathe, Neha A.; Kestenbaum, Bryan R.; Himmelfarb, Jonathan; Johnson, Nicholas J.; Shapiro, Nathan I.; Douglas, Ivor S.; Hough, Catherine L.; Bhatraju, Pavan K.
- Abstract
The article focuses on investigating the interaction of acute kidney injury (AKI) with resuscitation strategies in sepsis, utilizing data from the Clovers trial. Topics discussed include the incidence of renal replacement therapy (RRT) in patients with and without AKI under liberal or restrictive fluid resuscitation protocols, the potential influence of fluid volume on clinical outcomes, and the limitations of prior observational studies in assessing fluid management in sepsis-associated AKI.
- Publication
American Journal of Respiratory & Critical Care Medicine, 2023, Vol 208, Issue 12, p1335
- ISSN
1073-449X
- Publication type
Article
- DOI
10.1164/rccm.202308-1448LE