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- Title
Rapidly developing facial and intertriginous hyperpigmentation with acral erythema after docetaxel infusion.
- Authors
Eryilmaz, Melek; Tazegul, Gokhan; Ünal, Betül; Müsri, Fatma; Güzel, Halil; Coşkun, Hasan; Eryılmaz, Melek Karakurt; Müsri, Fatma Yalçin; Güzel, Halil Göksel; Coşkun, Hasan Şenol
- Abstract
Sir, Skin reactions related to docetaxel are diverse: alopecia, mucositis, stomatitis, xerosis, pruritus, urticaria, angioedema, acral erythema, maculopapular rashes, desquamation, pseudoscleroderma, lupus-like reactions, hypersensitivity reactions, photolichenoid eruption, and erythema multiforme major were previously reported.[[1]] Rare cases of persistent serpentine supravenous hyperpigmented eruption, radiation recall dermatitis, recall inflammatory skin reactions, and photo recall phenomenon were previously described as well.[[2]] Herein, we present the first case of painless acral erythema and rapidly developing intertriginous and facial hyperpigmentation induced by docetaxel in a patient with metastatic lung adenocarcinoma. Following the second cycle of docetaxel (75 mg/m2), 3 days after the administration, the patient developed painless erythema and swelling on hands and feet within an hour; after that, he developed bilateral axillary inguinal and facial hyperpigmentation in a matter of few hours [Figure 1]a, [Figure 1]b, [Figure 1]c.
- Subjects
HYPERPIGMENTATION; DOCETAXEL; ERYTHEMA
- Publication
Journal of Cancer Research & Therapeutics, 2021, Vol 17, Issue 1, p293
- ISSN
0973-1482
- Publication type
case study
- DOI
10.4103/jcrt.JCRT_385_17