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- Title
Multinodular fibroepithelioma of Pinkus with an isolated focus of evolving basal cell carcinoma in chronic lymphedematous lower limb.
- Authors
Majumdar, Kaushik; Khurana, Ujjawal; Goel, Garima; Joshi, Deepti; Kapoor, Neelkamal; Asati, Dinesh
- Abstract
Fibroepithelioma of Pinkus (FEP) is a rare, indolent variant of basal cell carcinoma (BCC) with a unique anastomosing type of epidermal hyperplasia. Certain benign and neoplastic conditions including BCC are known to develop in a setting of chronic lymphedema. We report for the 1st time the histological spectrum of evolution of a large exophytic multinodular FEP, bearing a single initiating focus of BCC, in preexisting chronic lymphedema of the lower limb. The lesion possibly evolved from long-standing local immune suppression, and clinically resembled a high-grade carcinoma. Oozing lymphatic fluid may interfere with the success of skin grafting following wide local excision in a lymphedematous limb, thus offering a challenging scenario from the management point of view.
- Subjects
BASAL cell carcinoma; LEG diseases; LYMPHEDEMA; LYMPHEDEMA diagnosis; DIAGNOSIS; PATIENTS
- Publication
Journal of Cancer Research & Therapeutics, 2017, Vol 13, Issue 6, p1038
- ISSN
0973-1482
- Publication type
case study
- DOI
10.4103/0973-1482.220454