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- Title
Cytotoxic Metabolites from the Soil-Derived Fungus Exophiala Pisciphila.
- Authors
Cui-Cui Wang; Hai-Zhou Liu; Ming Liu; Yu-Yan Zhang; Tian-Tian Li; Xiu-Kun Lin
- Abstract
A new polyketide compound 1 and a new naturally occurring chromone derivative 2, along with two known indole alkaloids 3-4 were characterized from the ethyl acetate extract of a soil-derived fungal strain, Exophiala pisciphila PHF-9. The structures of compounds 1-4 were established by detailed spectroscopic analysis and comparison with literature data. The absolute configuration of 1 was determined by a modified Mosher's method. Compound 1 exhibited moderate cytotoxicity against A-549, Hela, PANC-28 and BEL-7402 cell lines.
- Subjects
METABOLITES; POLYKETIDES; ALKALOIDS; CELL lines; FUNGI
- Publication
Molecules, 2011, Vol 16, Issue 4, p2796
- ISSN
1420-3049
- Publication type
Article
- DOI
10.3390/molecules16042796