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- Title
Association between ambient fine particulate matter and adult outpatient visits for rheumatoid arthritis in Beijing, China.
- Authors
Chen, Hongbo; Wu, Junhui; Wang, Mengying; Wang, Siyue; Wang, Jiating; Yu, Huan; Hu, Yonghua; Shang, Shaomei
- Abstract
The association between fine particulate matter (PM2.5) and rheumatoid arthritis (RA) is currently unclear, especially in Beijing, a city with severe air pollution. Our study aimed to explore the relationship between short-term outdoor exposure to PM2.5 and RA outpatient visits using a time-series analysis in Beijing. We used the Beijing's Medical Claims for Employees database to identify patients with RA in 2010–2012. A generalized additive model with a Poisson link was used to estimate the percentage change in RA outpatient visits after the PM2.5 concentration increased by 10 μg/m3. From January 1, 2010, to June 30, 2012, a total of 541,061 RA outpatient visits were identified. During the study period, the average daily (standard deviation) concentration of PM2.5 was 99.5 (75.3) µg/m3. A 10 µg/m3 increase in PM2.5 concentration was correlated with a 0.21% (95% CI, 0.18–0.23%) increase in outpatient visits for RA on the same day. A significant association for the cumulative effect of PM2.5 was found, and the largest significant association was observed for a lag of 0–3 days (0.26%; 95% CI, 0.23–0.29%). Stratified analyses revealed that females (0.29%, 95% CI: 0.26–0.33%) and 18–65 years old patients (0.29%, 95% CI: 0.25–0.32%) were most susceptible to the effects of PM2.5 exposure. The current findings showed that short-term exposure to PM2.5 was followed by an increase in the number of outpatient visits for RA in Beijing. Future studies should investigate the mechanisms underlying this association.
- Subjects
BEIJING (China); PARTICULATE matter; RHEUMATOID arthritis; PERCENTILES; TIME series analysis; AIR pollution; OUTPATIENTS
- Publication
International Journal of Biometeorology, 2023, Vol 67, Issue 1, p149
- ISSN
0020-7128
- Publication type
Article
- DOI
10.1007/s00484-022-02393-0