We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Impact of COVID-19 on Antimicrobial Consumption and Spread of Multidrug-Resistance in Bacterial Infections.
- Authors
Jeon, Kibum; Jeong, Seri; Lee, Nuri; Park, Min-Jeong; Song, Wonkeun; Kim, Han-Sung; Kim, Hyun Soo; Kim, Jae-Seok
- Abstract
The spread of COVID-19 pandemic may have affected antibiotic consumption patterns and the prevalence of colonized or infected by multidrug-resistant (MDR) bacteria. We investigated the differences in the consumption of antibiotics easily prone to resistance and the prevalence of MDR bacteria during the COVID-19 pandemic (March 2020 to September 2021) compared to in the pre-pandemic period (March 2018 to September 2019). Data on usage of antibiotics and infections caused by methicillin-resistant Staphylococcus aureus (MRSA), vancomycin-resistant Enterococcus (VRE), carbapenem-resistant Enterobacteriaceae (CRE), carbapenem-resistant Acinetobacter baumannii (CRAB), and carbapenem-resistant Pseudomonas aeruginosa (CRPA) were obtained from hospitalized patients in four university hospitals. The consumption of penicillin with β-lactamase inhibitors (3.4% in ward, 5.8% in intensive care unit (ICU)), and carbapenems (25.9% in ward, 12.1% in ICU) increased during the pandemic period. The prevalence of MRSA (4.7%), VRE (49.0%), CRE (22.4%), and CRPA (20.1%) isolated in clinical samples from the ward and VRE (26.7%) and CRE (36.4%) isolated in clinical samples from the ICU were significantly increased, respectively. Meanwhile, only the prevalence of CRE (38.7%) isolated in surveillance samples from the ward increased. The COVID-19 pandemic is associated with increased consumption of antibiotics and has influenced the prevalence of infections caused by MDR isolates.
- Subjects
CARBAPENEM-resistant bacteria; BACTERIAL diseases; MULTIDRUG resistance; METHICILLIN-resistant staphylococcus aureus; ACINETOBACTER baumannii
- Publication
Antibiotics (2079-6382), 2022, Vol 11, Issue 4, pN.PAG
- ISSN
2079-6382
- Publication type
Article
- DOI
10.3390/antibiotics11040535