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Development of a HPLC Method for Analysis of a Combination of Clofazimine, Isoniazid, Pyrazinamide, and Rifampicin Incorporated into a Dermal Self-Double-Emulsifying Drug Delivery System.
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- Methods & Protocols, 2023, v. 6, n. 6, p. 104, doi. 10.3390/mps6060104
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- Publication type:
- Article
Varying degrees of homostructurality in a series of cocrystals of antimalarial drug 11‐azaartemisinin with salicylic acids.
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- Acta Crystallographica Section C: Structural Chemistry, 2021, v. 77, n. 6, p. 262, doi. 10.1107/S2053229621004460
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- Publication type:
- Article
Cocrystals of the antimalarial drug 11‐azaartemisinin with three alkenoic acids of 1:1 or 2:1 stoichiometry.
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- Acta Crystallographica Section C: Structural Chemistry, 2018, v. 74, n. 6, p. 742, doi. 10.1107/S2053229618006320
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- Publication type:
- Article
Antimalarial and antitumour activities of the steroidal quinone-methide celastrol and its combinations with artemiside, artemisone and methylene blue.
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- Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.988748
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- Article
The evaluation of ADME and pharmacokinetic properties of decoquinate derivatives for the treatment of malaria.
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- Frontiers in Pharmacology, 2022, v. 13, p. 01, doi. 10.3389/fphar.2022.957690
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- Article
The Science of Selecting Excipients for Dermal Self-Emulsifying Drug Delivery Systems.
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- Pharmaceutics, 2023, v. 15, n. 4, p. 1293, doi. 10.3390/pharmaceutics15041293
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- Article
The Development of Dermal Self-Double-Emulsifying Drug Delivery Systems: Preformulation Studies as the Keys to Success.
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- Pharmaceuticals (14248247), 2023, v. 16, n. 10, p. 1348, doi. 10.3390/ph16101348
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- Publication type:
- Article
A Drug Repurposing Approach for Antimalarials Interfering with SARS-CoV-2 Spike Protein Receptor Binding Domain (RBD) and Human Angiotensin-Converting Enzyme 2 (ACE2).
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- Pharmaceuticals (14248247), 2021, v. 14, n. 10, p. 954, doi. 10.3390/ph14100954
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- Article
Combining computational and experimental evidence on the activity of antimalarial drugs on papain‐like protease of SARS‐CoV‐2: A repurposing study.
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- Chemical Biology & Drug Design, 2023, v. 101, n. 4, p. 809, doi. 10.1111/cbdd.14187
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- Article
Adapting Clofazimine for Treatment of Cutaneous Tuberculosis by Using Self-Double-Emulsifying Drug Delivery Systems.
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- Antibiotics (2079-6382), 2022, v. 11, n. 6, p. 806, doi. 10.3390/antibiotics11060806
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- Article
Formulation of Natural Oil Nano-Emulsions for the Topical Delivery of Clofazimine, Artemisone and Decoquinate.
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- Pharmaceutical Research, 2018, v. 35, n. 10, p. 1, doi. 10.1007/s11095-018-2471-9
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- Article
A single amino acid residue can determine the sensitivity of SERCAs to artemisinins.
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- Nature Structural & Molecular Biology, 2012, v. 19, n. 2, p. 264, doi. 10.1038/nsmb0212-264
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- Article
A single amino acid residue can determine the sensitivity of SERCAs to artemisinins.
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- Nature Structural & Molecular Biology, 2005, v. 12, n. 7, p. 628, doi. 10.1038/nsmb947
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- Article
Anticancer Properties of Distinct Antimalarial Drug Classes.
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- PLoS ONE, 2013, v. 8, n. 12, p. 1, doi. 10.1371/journal.pone.0082962
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- Publication type:
- Article
Glucocorticosteroids in Nano-Sterically Stabilized Liposomes Are Efficacious for Elimination of the Acute Symptoms of Experimental Cerebral Malaria.
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- PLoS ONE, 2013, v. 8, n. 8, p. 1, doi. 10.1371/journal.pone.0072722
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- Publication type:
- Article
Expression in Yeast Links Field Polymorphisms in PfATP6 to in Vitro Artemisinin Resistance and Identifies New Inhibitor Classes.
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- Journal of Infectious Diseases, 2013, v. 208, n. 3, p. 468, doi. 10.1093/infdis/jit171
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- Publication type:
- Article
Low-Temperature X-ray Crystal-Structure Analysis of the Thermally Unstable Lithiated 2-Butenyl tert-Butyl Sulfide: A comparison with model ab initio MO calculations.
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- Helvetica Chimica Acta, 1988, v. 71, n. 2, p. 299, doi. 10.1002/hlca.19880710202
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- Article
Anti-Melanoma Activities of Artemisone and Prenylated Amino-Artemisinins in Combination With Known Anticancer Drugs.
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- Frontiers in Pharmacology, 2020, v. 11, p. N.PAG, doi. 10.3389/fphar.2020.558894
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- Article
Accumulation of TB-Active Compounds in Murine Organs Relevant to Infection by Mycobacterium tuberculosis.
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- Frontiers in Pharmacology, 2020, p. 1, doi. 10.3389/fphar.2020.00724
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- Publication type:
- Article
Control of 11-Aza:4-X-SalA Cocrystal Polymorphs Using Heteroseeds That Switch On/Off Halogen Bonding.
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- Crystals (2073-4352), 2022, v. 12, n. 10, p. 1368, doi. 10.3390/cryst12101368
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- Article
Synthesis of Cyclic Hexapeptides Based on the Antibiotic Cyclic Decapeptide Loloatin C by an in situ Indirect Cyclization Method.
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- European Journal of Organic Chemistry, 2004, v. 2004, n. 1, p. 38, doi. 10.1002/ejoc.200300477
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- Article
Elucidation of the Solution Conformations of Loloatin C by NMR Spectroscopy and Molecular Simulation.
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- European Journal of Organic Chemistry, 2004, v. 2004, n. 1, p. 31, doi. 10.1002/ejoc.200300476
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- Publication type:
- Article
Stereoselective Preparation of 10α- and 10β-Aryl Derivatives of Dihydroartemisinin.
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- European Journal of Organic Chemistry, 2003, v. 2003, n. 11, p. 2098, doi. 10.1002/ejoc.200300064
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- Publication type:
- Article
In Vitro versus in Mice: Efficacy and Safety of Decoquinate and Quinoline- O -Carbamate Derivatives against Experimental Infection with Neospora caninum Tachyzoites.
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- Pathogens, 2023, v. 12, n. 3, p. 447, doi. 10.3390/pathogens12030447
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- Publication type:
- Article
In Vitro Activity of the Arylaminoartemisinin GC012 against Helicobacter pylori and Its Effects on Biofilm.
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- Pathogens, 2022, v. 11, n. 7, p. N.PAG, doi. 10.3390/pathogens11070740
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- Publication type:
- Article
Titelbild: Artemisone—A Highly Active Antimalarial Drug of the Artemisinin Class (Angew. Chem. 13/2006).
- Published in:
- Angewandte Chemie, 2006, v. 118, n. 13, p. 2041, doi. 10.1002/ange.200690045
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- Publication type:
- Article
Artemisone—A Highly Active Antimalarial Drug of the Artemisinin ClassWork at the HKUST was funded by Bayer AG Central Research, Leverkusen, the Institute of Molecular Technology for Drug Discovery and Synthesis through the HKSAR University Grants Committee Areas of Excellence Fund, and the HKSAR Research Grants Council through the Competitive Earmarked Research Grants Scheme. The Medicines for Malaria Venture (MMV), Geneva, also provided financial support of the work at Bayer, and through Bayer at HKUST and other centers. Dr. W. Collins (Centers for Disease Control, Atlanta) supplied P. falciparum FVO strain used for the primate studies.
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- Angewandte Chemie, 2006, v. 118, n. 13, p. 2136, doi. 10.1002/ange.200503071
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- Article
Reply to Comments on "Highly Antimalaria-Active Artemisinin Derivatives: Biological Activity Does Not Correlate with Chemical Reactivity".
- Published in:
- Angewandte Chemie, 2005, v. 117, n. 14, p. 2100, doi. 10.1002/ange.200462723
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- Publication type:
- Article
Highly Antimalaria-Active Artemisinin Derivatives: Biological Activity Does Not Correlate with Chemical Reactivity ( This work was supported by grants from Bayer AG (Leverkusen, Germany) and by the Government of the HKSAR University Grants Council (grant no. HKUST 6091/02P). )
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- Angewandte Chemie, 2004, v. 116, n. 11, p. 1405, doi. 10.1002/ange.200352343
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- Article
In vitro study of the anti-cancer effects of artemisone alone or in combination with other chemotherapeutic agents.
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- 2011
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- Publication type:
- journal article
An in vitro ADME and in vivo Pharmacokinetic Study of Novel TB-Active Decoquinate Derivatives.
- Published in:
- Frontiers in Pharmacology, 2019, p. N.PAG, doi. 10.3389/fphar.2019.00120
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- Article
The First Examples of Enantiomerically Pure Diphosphane Dioxides-( R<sub>P</sub>, R<sub>P</sub>)- and ( S<sub>P</sub>, S<sub>P</sub>)-1,2-Di- ter-butyl-1,2-diphenyldiphosphane 1,2-Dioxides, and ( R<sub>P</sub>)- and ( S<sub>P</sub>)-1- tert-Butyl-1,2,2-triphenyldiphosphane 1,2-Dioxides
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- Chemistry - A European Journal, 1997, v. 3, n. 12, p. 2052, doi. 10.1002/chem.19970031221
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- Publication type:
- Article
Efficacies and ADME properties of redox active methylene blue and phenoxazine analogues for use in new antimalarial triple drug combinations with amino-artemisinins.
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- Frontiers in Pharmacology, 2024, p. 1, doi. 10.3389/fphar.2023.1308400
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- Publication type:
- Article
Topical Delivery of Artemisone, Clofazimine and Decoquinate Encapsulated in Vesicles and Their In vitro Efficacy Against Mycobacterium tuberculosis.
- Published in:
- AAPS PharmSciTech, 2019, v. 20, n. 1, p. 1, doi. 10.1208/s12249-018-1251-5
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- Article
Cover Picture: Artemisone—A Highly Active Antimalarial Drug of the Artemisinin Class (Angew. Chem. Int. Ed. 13/2006).
- Published in:
- Angewandte Chemie International Edition, 2006, v. 45, n. 13, p. 1989, doi. 10.1002/anie.200690045
- By:
- Publication type:
- Article
Artemisone—A Highly Active Antimalarial Drug of the Artemisinin ClassWork at the HKUST was funded by Bayer AG Central Research, Leverkusen, the Institute of Molecular Technology for Drug Discovery and Synthesis through the HKSAR University Grants Committee Areas of Excellence Fund, and the HKSAR Research Grants Council through the Competitive Earmarked Research Grants Scheme. The Medicines for Malaria Venture (MMV), Geneva, also provided financial support of the work at Bayer, and through Bayer at HKUST and other centers. Dr. W. Collins (Centers for Disease Control, Atlanta) supplied P. falciparum FVO strain used for the primate studies.
- Published in:
- Angewandte Chemie International Edition, 2006, v. 45, n. 13, p. 2082, doi. 10.1002/anie.200503071
- By:
- Publication type:
- Article
Reply to Comments on 'Highly Antimalaria-Active Artemisinin Derivatives: Biological Activity Does Not Correlate with Chemical Reactivity'.
- Published in:
- Angewandte Chemie International Edition, 2005, v. 44, n. 14, p. 2064, doi. 10.1002/anie.200462723
- By:
- Publication type:
- Article
Highly Antimalaria-Active Artemisinin Derivatives: Biological Activity Does Not Correlate with Chemical Reactivity ( This work was supported by grants from Bayer AG (Leverkusen, Germany) and by the Government of the HKSAR University Grants Council (grant no. HKUST 6091/02P). )
- Published in:
- Angewandte Chemie International Edition, 2004, v. 43, n. 11, p. 1381, doi. 10.1002/anie.200352343
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- Publication type:
- Article
Assessment of the Activity of Decoquinate and Its Quinoline- O -Carbamate Derivatives against Toxoplasma gondii In Vitro and in Pregnant Mice Infected with T. gondii Oocysts.
- Published in:
- Molecules, 2021, v. 26, n. 21, p. 6393, doi. 10.3390/molecules26216393
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- Publication type:
- Article
Facile Preparation of N-Glycosylated 10-Piperazinyl Artemisinin Derivatives and Evaluation of Their Antimalarial and Cytotoxic Activities.
- Published in:
- Molecules, 2018, v. 23, n. 7, p. 1713, doi. 10.3390/molecules23071713
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- Publication type:
- Article
The evaluation of the anti‐cancer drug elesclomol that forms a redox‐active copper chelate as a potential anti‐tubercular drug.
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- IUBMB Life, 2019, v. 71, n. 5, p. 532, doi. 10.1002/iub.2002
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- Article
Preliminary Evaluation of Artemisinin–Cholesterol Conjugates as Potential Drugs for the Treatment of Intractable Forms of Malaria and Tuberculosis.
- Published in:
- ChemMedChem, 2018, v. 13, n. 1, p. 67, doi. 10.1002/cmdc.201700579
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- Publication type:
- Article
Activities of 11-Azaartemisinin and N-Sulfonyl Derivatives against Asexual and Transmissible Malaria Parasites.
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- ChemMedChem, 2017, v. 12, n. 24, p. 2086, doi. 10.1002/cmdc.201700599
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- Publication type:
- Article
Activities of 11-Azaartemisinin and N-Sulfonyl Derivatives against Neospora caninum and Comparative Cytotoxicities.
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- ChemMedChem, 2017, v. 12, n. 24, p. 2094, doi. 10.1002/cmdc.201700600
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- Publication type:
- Article
Methylene Homologues of Artemisone: An Unexpected Structure–Activity Relationship and a Possible Implication for the Design of C10-Substituted Artemisinins.
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- ChemMedChem, 2016, v. 11, n. 13, p. 1469, doi. 10.1002/cmdc.201600011
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- Article
Interactions between Artemisinins and other Antimalarial Drugs in Relation to the Cofactor Model-A Unifying Proposal for Drug Action.
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- ChemMedChem, 2012, v. 7, n. 12, p. 2204, doi. 10.1002/cmdc.201200383
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- Publication type:
- Article
A Partial Convergence in Action of Methylene Blue and Artemisinins: Antagonism with Chloroquine, a Reversal with Verapamil, and an Insight into the Antimalarial Activity of Chloroquine.
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- ChemMedChem, 2011, v. 6, n. 9, p. 1603, doi. 10.1002/cmdc.201100184
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- Publication type:
- Article
Reactions of Antimalarial Peroxides with Each of Leucomethylene Blue and Dihydroflavins: Flavin Reductase and the Cofactor Model Exemplified.
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- ChemMedChem, 2011, v. 6, n. 2, p. 279, doi. 10.1002/cmdc.201000508
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- Publication type:
- Article
Interaction of Artemisinins with Oxyhemoglobin Hb-Fe<sup>II</sup>, Hb-Fe<sup>II</sup>, CarboxyHb-Fe<sup>II</sup>, Heme-Fe<sup>II</sup>, and Carboxyheme Fe<sup>II</sup>: Significance for Mode of Action and Implications for Therapy of Cerebral Malaria.
- Published in:
- ChemMedChem, 2009, v. 4, n. 12, p. 2045, doi. 10.1002/cmdc.200900342
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- Article
Cover Picture: Interaction of Artemisinins with Oxyhemoglobin Hb-Fe<sup>II</sup>, Hb-Fe<sup>II</sup>, CarboxyHb-Fe<sup>II</sup>, Heme-Fe<sup>II</sup>, and Carboxyheme Fe<sup>II</sup>: Significance for Mode of Action and Implications for Therapy of Cerebral Malaria (ChemMedChem 12/2009)
- Published in:
- ChemMedChem, 2009, v. 4, n. 12, p. 1957, doi. 10.1002/cmdc.200990056
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- Article