We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Multisystem Inflammatory Syndrome in Children (Mis-C): Addition of another Apprehension in Sars-CoV-2 Pandemic.
- Authors
Mallik, Santanu; Kumar, Nilesh
- Abstract
Amidst the SARS-CoV-2 pandemic throughout the world with millions of active infections and deaths, few unprecedented cluster reports on children related to coronavirus infection are emerging as serious issue of concern. World Health Organization has termed this condition as Multisystem Inflammatory Syndrome in Children (MIS-C). MIS-C is a condition where different body parts or vital organs become inflamed and in children’s the condition is prominently associated with inflamed blood vessel or Kawasaki diseases, toxic shock syndrome or toxins produced in body due to overgrowth of a microbe leading to shock, fever, conjunct ivitis, abdominal pain, multi organ failure. The present day data confirms that SARS-CoV-2 has mild effect on children or infants. But few incidences have been reported from United Kingdom, United States, Italy, Spain, India and few other countries, that children’s with median age group of 11 years were admitted to hospitals with multisystem inflammatory conditions during this pandemic period from the beginning. Different observational studies suggested that such conditions developed in children are mediated by the development of acquired immunity of post infection rather than the direct viral infection. But the first MIS-C patient from India, a eightyear old boy from Tamilnadu is having confirmed coronavirus infection. Furthermore, during SARS in 2005, it was evidenced that HCoVâ€NL63 has been also associated with Kawasaki disease. Thus relationship of MIS-C with SARS-CoV-2 cannot be disregard. Although, the numbers of reporting of MIS-C is very less but it may become serious matter of concern in upcoming days. Considering the severity of situation, the World Health Organization has constituted a working group of experts from different part of the world. They will generate protocol of collection, collation and analysis of data from around the world where India is likely to be selected as surveillance site for MIS-C data.
- Subjects
INDIA; SARS-CoV-2; PANDEMICS; TOXIC shock syndrome; WORLD Health Organization; VIRUS diseases; SYNDROMES
- Publication
International Journal of Pharmacy & Life Sciences, 2020, Vol 11, Issue 7, p43
- ISSN
0976-7126
- Publication type
Article