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- Title
Associations Among Sex, Cognitive Ability, and Autism Symptoms in Individuals with Down Syndrome.
- Authors
del Hoyo Soriano, Laura; Sterling, Audra; Edgin, Jamie; Hamilton, Debra R.; Berry-Kravis, Elizabeth; Dimachkie Nunnally, Amanda; Thurman, Angela John; Abbeduto, Leonard
- Abstract
This study explores sex-differences in (a) rates and profiles of autism symptoms as well as in (b) the contribution of intellectual quotient (IQ) to autism symptom presentation in Down syndrome (DS). Participants were 40 males and 38 females with DS, aged 6 to 23 years. Autism symptoms were rated through the Autism Diagnostic Observation Schedule-Second Edition (ADOS-2). Results show no sex differences in the ADOS-2 Calibrated Severity Scores (CSS). However, only females with DS who are classified as DS-Only have higher scores on verbal IQ than those classified as DS + autism. Furthermore, associations between IQ and all CSSs are found for females, but not for males. Findings suggest that verbal cognition may play differential roles for females and males with DS.
- Subjects
DOWN syndrome; COGNITION; SEX distribution; AUTISM; RESEARCH funding; SYMPTOMS
- Publication
Journal of Autism & Developmental Disorders, 2024, Vol 54, Issue 1, p301
- ISSN
0162-3257
- Publication type
Article
- DOI
10.1007/s10803-022-05779-6