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- Title
Alcohol use and non-adherence to antiretroviral therapy in HIV-infected patients in West Africa.
- Authors
Jaquet, Antoine; Ekouevi, Didier K.; Bashi, Jules; Aboubakrine, Maiga; Messou, Eugène; Maiga, Moussa; Traore, Hamar Alassane; Zannou, Marcel Djimon; Guehi, Calixte; Ba‐Gomis, Franck Olivier; Minga, Albert; Allou, Gérard; Eholie, Serge Paul; Bissagnene, Emmanuel; Sasco, Annie J.; Dabis, Francois
- Abstract
Aim To investigate the association between alcohol use and adherence to highly active antiretroviral treatment (HAART) among human immunodeficiency virus (HIV)-infected patients in subSaharan Africa. Design and setting Cross-sectional survey conducted in eight adult HIV treatment centres from Benin, Côte d'Ivoire and Mali. Participants and measurements During a 4-week period, health workers administered the Alcohol Use Disorders Identification Test to HAART-treated patients and assessed treatment adherence using the AIDS Clinical Trials Group follow-up questionnaire. Findings A total of 2920 patients were enrolled with a median age of 38 years [interquartile range (IQR) 32–45 years] and a median duration on HAART of 3 years (IQR 1–4 years). Overall, 91.8% of patients were identified as adherent to HAART. Non-adherence was associated with current drinking [odds ratio (OR) 1.4; 95% confidence interval (CI) 1.1–2.0], hazardous drinking (OR 4.7; 95% CI 2.6–8.6) and was associated inversely with a history of counselling on adherence (OR 0.7; 95% CI 0.5–0.9). Conclusions Alcohol consumption and hazardous drinking is associated with non-adherence to HAART among HIV-infected patients from West Africa. Adult HIV care programmes should integrate programmes to reduce hazardous and harmful drinking.
- Subjects
SUB-Saharan Africa; ALCOHOL drinking; HIGHLY active antiretroviral therapy; HIV-positive persons; IMMUNE adherence reaction; HIV infections; THERAPEUTICS; ANTIRETROVIRAL agents; ALCOHOLISM; PEOPLE with alcoholism; MEDICAL care; CROSS-sectional method
- Publication
Addiction, 2010, Vol 105, Issue 8, p1416
- ISSN
0965-2140
- Publication type
Article
- DOI
10.1111/j.1360-0443.2010.02978.x