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- Title
Using Glycosylated Hemoglobin to Define the Metabolic Syndrome in United States Adults.
- Authors
Kwok Leung Ong; Tso, Annette W. K.; Lam, Karen S. L.; Cherny, Stacey S.; Pak Chung Sham; Cheung, Bernard M. Y.
- Abstract
OBJECTIVE -- To compare the use of GHb and fasting plasma glucose (FPG) to define the metabolic syndrome (MetS). RESEARCH DESIGN AND METHODS-- Data from the U.S. National Health and Nutrition Examination Survey 1999-2006 were used. MetS was defined using the consensus criteria in 2009. Raised blood glucose was defined as either FPG ≥100 mg/dl (5.6 mmol/1) or GHb ≥5.7%. RESULTS -- In 2003-2006, there was 91.3% agreement between GHb and FPG when either was used to define MetS. The agreement was good irrespective of age, sex, race/ethnicity, BMI, and diabetes status (≥87.4%). Similar results were found in 1999-2002. Among subjects without diabetes, only the use of GHb alone, but not FPG, resulted in significant association with cardiovascular diseases (odds ratio 1.45, P = 0.005). CONCLUSIONS -- Using GHb instead of FPG to define MetS is feasible. It also identifies individuals with increased cardiovascular risk.
- Subjects
UNITED States; GLYCOSYLATED hemoglobin; METABOLIC syndrome; PEOPLE with diabetes; MEDICAL care; HEALTH
- Publication
Diabetes Care, 2010, Vol 33, Issue 8, p1856
- ISSN
0149-5992
- Publication type
Article
- DOI
10.2337/dc10-0190