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- Title
1-(2-Chloroethyl)-Cyclohexyl-Nitrosourea-Induced Remission in Essential Thrombocythemia.
- Authors
Leoni, F.; Grossi, A.; Ferrini, Rossi
- Abstract
14 patients with essential thrombocythemia (ET) and 1 patient with agnogenic myeloid metaplasia received (1-(2-chloroethyl)-cyclohexyl-nitrosourea (CCNU), 80 mg/m2, p.o., in a single dose once a month up to three times. Remission was achieved in 13 patients (86.6%) and easily maintained by low-dose busulfan (2 mg twice a week). The data on the treatment of ET reported in the literature have been reviewed and compared to our results. Copyright © 1983 S. Karger AG, Basel
- Publication
Acta Haematologica, 1983, Vol 69, Issue 3, p180
- ISSN
0001-5792
- Publication type
Article
- DOI
10.1159/000206885